8:00 AM | | | | 187 | | Role of predictive ADME and toxicity modeling in drug discovery
Alan G.E. Wilson | |
8:45 AM | | | | 188 | | Structural alerts for hepatotoxicity
William J. Egan Marco Pintore, Nadège Piclin, Han van de Waterbeemd | |
9:15 AM | | | | 189 | | Boosting the limits in early ADME prediction
Jacques R. Chretien | |
9:45 AM | | | | 190 | | Challenges in predictive ADMET: imperfect data in an imperfect world
Stephen R Johnson | |
10:15 AM | | | | 191 | | Classifying the mutagenicity of two diverse sets of organic compounds using Ames test data for Salmonella typhimurium TA100 and TA98
Brian E. Mattioni Peter C. Jurs, David T. Stanton | |
10:45 AM | | | | 192 | | Development of an in silico predictive protocol for hERG liability
Hongwu Wang Vincent Madison, Xue-Song Zhang, Steve Sorota | |
11:15 AM | | | | 193 | | Using targeted measurements to improve the accuracy of predictions of molecular physical properties
Robert S. DeWitte Eduard Kolovanov | |
11:45 AM | | | | 194 | | The failure of in vitro ADME properties to correctly determine in vivo outcomes
Daniel A. Norris Troy Bremer, Kevin Holme, Glen Leesman, Manish Sud | |
12:15 PM | | | | 195 | | Challenges for in silico modeling of ADME data
Terry R Stouch | |